node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDM46562.1 | EDM48477.1 | MDG893_12213 | MDG893_18082 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.986 |
EDM46562.1 | rlmE | MDG893_12213 | MDG893_04122 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.987 |
EDM46562.1 | rplM | MDG893_12213 | MDG893_12795 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.986 |
EDM46562.1 | rplX | MDG893_12213 | MDG893_13759 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.986 |
EDM46562.1 | rpoB | MDG893_12213 | MDG893_13859 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.419 |
EDM46562.1 | rpsJ | MDG893_12213 | MDG893_13829 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.564 |
EDM48477.1 | EDM46562.1 | MDG893_18082 | MDG893_12213 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.986 |
EDM48477.1 | EDM49010.1 | MDG893_18082 | MDG893_06234 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | COG0223 Methionyl-tRNA formyltransferase. | 0.989 |
EDM48477.1 | fmt | MDG893_18082 | MDG893_18077 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.997 |
EDM48477.1 | rlmE | MDG893_18082 | MDG893_04122 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.985 |
EDM48477.1 | rlmN | MDG893_18082 | MDG893_08150 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Predicted Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.965 |
EDM48477.1 | rplM | MDG893_18082 | MDG893_12795 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.967 |
EDM48477.1 | rplX | MDG893_18082 | MDG893_13759 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.974 |
EDM48477.1 | rpoB | MDG893_18082 | MDG893_13859 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.974 |
EDM48477.1 | rpsJ | MDG893_18082 | MDG893_13829 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.991 |
EDM48477.1 | thiI | MDG893_18082 | MDG893_19639 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.968 |
EDM49010.1 | EDM48477.1 | MDG893_06234 | MDG893_18082 | COG0223 Methionyl-tRNA formyltransferase. | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.989 |
EDM49010.1 | fmt | MDG893_06234 | MDG893_18077 | COG0223 Methionyl-tRNA formyltransferase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.538 |
EDM49010.1 | rlmN | MDG893_06234 | MDG893_08150 | COG0223 Methionyl-tRNA formyltransferase. | Predicted Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.586 |
EDM49010.1 | thiI | MDG893_06234 | MDG893_19639 | COG0223 Methionyl-tRNA formyltransferase. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.440 |