STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDO84848.1Dihydrofolate reductase. (184 aa)    
Predicted Functional Partners:
SDO84889.1
Two-component system, OmpR family, sensor histidine kinase VanS.
       0.773
SDO84935.1
Two-component system, OmpR family, response regulator VanR.
       0.773
SDP55805.1
Dihydrofolate reductase.
  
     0.747
SDO96826.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.706
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.644
SDO84972.1
D-alanyl-D-alanine carboxypeptidase.
       0.549
SDO85007.1
VanZ like family protein.
       0.549
SDP55756.1
Catechol 2,3-dioxygenase.
  
    0.533
SDO89243.1
RibD C-terminal domain-containing protein.
 
     0.504
Your Current Organism:
Phycicoccus dokdonensis
NCBI taxonomy Id: 443156
Other names: CCUG 54521, DSM 22329, KCTC 19248, P. dokdonensis, Phycicoccus dokdonensis Yoon et al. 2008, strain DS-8
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.