node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDP04914.1 | SDP11145.1 | SAMN04489867_1276 | SAMN04489867_1447 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate aminotransferase. | 0.817 |
SDP04914.1 | SDP59757.1 | SAMN04489867_1276 | SAMN04489867_3071 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.859 |
SDP04914.1 | SDP63620.1 | SAMN04489867_1276 | SAMN04489867_3234 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Alanine-synthesizing transaminase. | 0.817 |
SDP04914.1 | coaA | SAMN04489867_1276 | SAMN04489867_2191 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase. | 0.919 |
SDP04914.1 | coaD | SAMN04489867_1276 | SAMN04489867_0369 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.962 |
SDP04914.1 | dut | SAMN04489867_1276 | SAMN04489867_0791 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.986 |
SDP04914.1 | metK | SAMN04489867_1276 | SAMN04489867_1275 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.938 |
SDP04914.1 | panC | SAMN04489867_1276 | SAMN04489867_3503 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.838 |
SDP04914.1 | priA | SAMN04489867_1276 | SAMN04489867_1274 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.839 |
SDP04914.1 | rpoZ | SAMN04489867_1276 | SAMN04489867_1277 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.831 |
SDP11145.1 | SDP04914.1 | SAMN04489867_1447 | SAMN04489867_1276 | Aspartate aminotransferase. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.817 |
SDP11145.1 | SDP59757.1 | SAMN04489867_1447 | SAMN04489867_3071 | Aspartate aminotransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.765 |
SDP11145.1 | SDP63620.1 | SAMN04489867_1447 | SAMN04489867_3234 | Aspartate aminotransferase. | Alanine-synthesizing transaminase. | 0.732 |
SDP11145.1 | metK | SAMN04489867_1447 | SAMN04489867_1275 | Aspartate aminotransferase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.759 |
SDP59757.1 | SDP04914.1 | SAMN04489867_3071 | SAMN04489867_1276 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.859 |
SDP59757.1 | SDP11145.1 | SAMN04489867_3071 | SAMN04489867_1447 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aspartate aminotransferase. | 0.765 |
SDP59757.1 | SDP63620.1 | SAMN04489867_3071 | SAMN04489867_3234 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Alanine-synthesizing transaminase. | 0.764 |
SDP63620.1 | SDP04914.1 | SAMN04489867_3234 | SAMN04489867_1276 | Alanine-synthesizing transaminase. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.817 |
SDP63620.1 | SDP11145.1 | SAMN04489867_3234 | SAMN04489867_1447 | Alanine-synthesizing transaminase. | Aspartate aminotransferase. | 0.732 |
SDP63620.1 | SDP59757.1 | SAMN04489867_3234 | SAMN04489867_3071 | Alanine-synthesizing transaminase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.764 |