STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fabH3-oxoacyl-[acyl-carrier-protein] synthase-3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (339 aa)    
Predicted Functional Partners:
SDP10034.1
[acyl-carrier-protein] S-malonyltransferase.
 
 
 0.999
SDP10154.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.999
SDO98780.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.970
SDO98750.1
Enoyl-[acyl-carrier-protein] reductase [NADH].
 
 
 0.966
SDP29989.1
Biotin carboxyl carrier protein /biotin carboxylase.
 
 
 0.964
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
 
 0.931
SDO91056.1
3-oxoacyl-[acyl-carrier protein] reductase.
 
 
 0.918
SDP73448.1
Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
 
 0.896
SDP72498.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.854
SDP16811.1
3-oxoacyl-[acyl-carrier protein] reductase.
 
 
 0.848
Your Current Organism:
Phycicoccus dokdonensis
NCBI taxonomy Id: 443156
Other names: CCUG 54521, DSM 22329, KCTC 19248, P. dokdonensis, Phycicoccus dokdonensis Yoon et al. 2008, strain DS-8
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