STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LONRF1Uncharacterized protein. (727 aa)    
Predicted Functional Partners:
DV515_00004256
Ubiquitin-like domain-containing protein.
   
  0.612
TRIP12
Uncharacterized protein.
    
 0.586
TP53BP1
Uncharacterized protein.
    
 0.576
DV515_00004586
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.553
BARD1
Uncharacterized protein.
    
 0.521
PAXIP1
Uncharacterized protein.
   
 0.519
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
     
0.499
PRKDC
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.498
XRCC6
SAP domain-containing protein.
     
 0.498
UBE2V2
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
 0.497
Your Current Organism:
Erythrura gouldiae
NCBI taxonomy Id: 44316
Other names: Chloebia gouldiae, Chloebia gouldiae gouldiae, E. gouldiae, Gouldian finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.