node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNH | FEN1 | ENSEGOP00005020607 | ENSEGOP00005018906 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.640 |
CCNH | VWA5B2 | ENSEGOP00005020607 | ENSEGOP00005006612 | CYCLIN domain-containing protein; Belongs to the cyclin family. | VWFA domain-containing protein. | 0.586 |
CCNH | XPA | ENSEGOP00005020607 | ENSEGOP00005014026 | CYCLIN domain-containing protein; Belongs to the cyclin family. | XPA_C domain-containing protein. | 0.788 |
CCNH | XPC | ENSEGOP00005020607 | ENSEGOP00005009142 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Uncharacterized protein. | 0.830 |
FEN1 | CCNH | ENSEGOP00005018906 | ENSEGOP00005020607 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | CYCLIN domain-containing protein; Belongs to the cyclin family. | 0.640 |
FEN1 | PARG | ENSEGOP00005018906 | ENSEGOP00005019395 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.691 |
FEN1 | VWA5B2 | ENSEGOP00005018906 | ENSEGOP00005006612 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | VWFA domain-containing protein. | 0.696 |
FEN1 | XPA | ENSEGOP00005018906 | ENSEGOP00005014026 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | XPA_C domain-containing protein. | 0.824 |
FEN1 | XPC | ENSEGOP00005018906 | ENSEGOP00005009142 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.669 |
FEN1 | XRCC5 | ENSEGOP00005018906 | ENSEGOP00005006569 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. | 0.728 |
FEN1 | XRCC6 | ENSEGOP00005018906 | ENSEGOP00005012445 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | SAP domain-containing protein. | 0.766 |
HPF1 | MACROH2A1 | ENSEGOP00005004883 | ENSEGOP00005015221 | Uncharacterized protein. | Macro domain-containing protein. | 0.420 |
HPF1 | MACROH2A2 | ENSEGOP00005004883 | ENSEGOP00005018830 | Uncharacterized protein. | macroH2A.2 histone. | 0.420 |
HPF1 | PARG | ENSEGOP00005004883 | ENSEGOP00005019395 | Uncharacterized protein. | Uncharacterized protein. | 0.514 |
HPF1 | VWA5B2 | ENSEGOP00005004883 | ENSEGOP00005006612 | Uncharacterized protein. | VWFA domain-containing protein. | 0.635 |
MACROH2A1 | HPF1 | ENSEGOP00005015221 | ENSEGOP00005004883 | Macro domain-containing protein. | Uncharacterized protein. | 0.420 |
MACROH2A1 | PARG | ENSEGOP00005015221 | ENSEGOP00005019395 | Macro domain-containing protein. | Uncharacterized protein. | 0.442 |
MACROH2A1 | VWA5B2 | ENSEGOP00005015221 | ENSEGOP00005006612 | Macro domain-containing protein. | VWFA domain-containing protein. | 0.613 |
MACROH2A1 | XRCC5 | ENSEGOP00005015221 | ENSEGOP00005006569 | Macro domain-containing protein. | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. | 0.553 |
MACROH2A1 | XRCC6 | ENSEGOP00005015221 | ENSEGOP00005012445 | Macro domain-containing protein. | SAP domain-containing protein. | 0.761 |