node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COQ2 | COQ3 | ENSEGOP00005005935 | ENSEGOP00005002447 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein. | 0.842 |
COQ2 | COQ4 | ENSEGOP00005005935 | ENSEGOP00005011326 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Coenzyme Q4. | 0.626 |
COQ2 | COQ5 | ENSEGOP00005005935 | ENSEGOP00005020893 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein. | 0.833 |
COQ2 | COQ6 | ENSEGOP00005005935 | ENSEGOP00005000871 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | FAD_binding_3 domain-containing protein. | 0.904 |
COQ2 | COQ7 | ENSEGOP00005005935 | ENSEGOP00005008299 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.631 |
COQ2 | COQ8A | ENSEGOP00005005935 | ENSEGOP00005003302 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | ABC1 domain-containing protein. | 0.634 |
COQ2 | COQ9 | ENSEGOP00005005935 | ENSEGOP00005009222 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. | 0.626 |
COQ2 | PDSS1 | ENSEGOP00005005935 | ENSEGOP00005007572 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.976 |
COQ2 | PDSS2 | ENSEGOP00005005935 | ENSEGOP00005000475 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Decaprenyl diphosphate synthase subunit 2. | 0.976 |
COQ2 | UQCRFS1 | ENSEGOP00005005935 | ENSEGOP00005017159 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.554 |
COQ3 | COQ2 | ENSEGOP00005002447 | ENSEGOP00005005935 | Uncharacterized protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.842 |
COQ3 | COQ4 | ENSEGOP00005002447 | ENSEGOP00005011326 | Uncharacterized protein. | Coenzyme Q4. | 0.776 |
COQ3 | COQ5 | ENSEGOP00005002447 | ENSEGOP00005020893 | Uncharacterized protein. | Uncharacterized protein. | 0.797 |
COQ3 | COQ6 | ENSEGOP00005002447 | ENSEGOP00005000871 | Uncharacterized protein. | FAD_binding_3 domain-containing protein. | 0.943 |
COQ3 | COQ7 | ENSEGOP00005002447 | ENSEGOP00005008299 | Uncharacterized protein. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.985 |
COQ3 | COQ8A | ENSEGOP00005002447 | ENSEGOP00005003302 | Uncharacterized protein. | ABC1 domain-containing protein. | 0.936 |
COQ3 | COQ9 | ENSEGOP00005002447 | ENSEGOP00005009222 | Uncharacterized protein. | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. | 0.784 |
COQ3 | PDSS1 | ENSEGOP00005002447 | ENSEGOP00005007572 | Uncharacterized protein. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.648 |
COQ3 | PDSS2 | ENSEGOP00005002447 | ENSEGOP00005000475 | Uncharacterized protein. | Decaprenyl diphosphate synthase subunit 2. | 0.589 |
COQ3 | UQCRFS1 | ENSEGOP00005002447 | ENSEGOP00005017159 | Uncharacterized protein. | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.598 |