STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRP3Uncharacterized protein. (692 aa)    
Predicted Functional Partners:
RRAS2
Uncharacterized protein.
    
 0.970
MRAS
Uncharacterized protein.
    
 0.969
HRAS
Uncharacterized protein.
    
 0.967
KRAS
Uncharacterized protein.
    
 0.967
NRAS
Uncharacterized protein.
    
 0.967
RASGRP1
Uncharacterized protein.
  
  
 
0.953
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 
  0.908
CACNA1D
Ca_chan_IQ domain-containing protein.
   
 
  0.883
CACNG4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
    
  0.877
CACNG3
Uncharacterized protein.
    
  0.877
Your Current Organism:
Erythrura gouldiae
NCBI taxonomy Id: 44316
Other names: Chloebia gouldiae, Chloebia gouldiae gouldiae, E. gouldiae, Gouldian finch
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.