LOC104587090 protein (Nelumbo nucifera) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Score

LOC104587090

NAC transcription factor 29-like. (308 aa)

Predicted Functional Partners:

LOC104600524

0.896

LOC104598979

0.894

LOC104607638

0.879

LOC104605100

0.814

LOC104597915

0.807

LOC104601469

0.807

LOC104586585

0.772

LOC104591292

0.772

LOC104596531

0.772

LOC104605292

0.772

Your Current Organism:

Nelumbo nucifera

NCBI taxonomy Id: 4432
Other names: Indian lotus, N. nucifera, Nelumbo nucifera Gaertn., padma, sacred lotus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC104586585	LOC104587090	A0A1U7YSW2	A0A1U7Z797	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	NAC transcription factor 29-like.	0.772
LOC104586585	LOC104591292	A0A1U7YSW2	A0A1U7ZB79	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.900
LOC104586585	LOC104596531	A0A1U7YSW2	A0A1U7ZPF9	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.	0.990
LOC104586585	LOC104597915	A0A1U7YSW2	A0A1U7ZW92	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	60S ribosomal protein L39.	0.986
LOC104586585	LOC104598979	A0A1U7YSW2	A0A1U8ABX0	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	40S ribosomal protein S21-2-like isoform X1.	0.998
LOC104586585	LOC104600524	A0A1U7YSW2	A0A1U8A5S9	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	40S ribosomal protein S29.	0.998
LOC104586585	LOC104601469	A0A1U7YSW2	A0A1U8A8Y2	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family.	0.987
LOC104586585	LOC104605100	A0A1U7YSW2	A0A1U8AK03	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family.	0.990
LOC104586585	LOC104605292	A0A1U7YSW2	A0A1U8ALS4	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.	0.990
LOC104586585	LOC104607638	A0A1U7YSW2	A0A1U8AU69	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	ubiquitin-60S ribosomal protein L40.	0.995
LOC104587090	LOC104586585	A0A1U7Z797	A0A1U7YSW2	NAC transcription factor 29-like.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.772
LOC104587090	LOC104591292	A0A1U7Z797	A0A1U7ZB79	NAC transcription factor 29-like.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.772
LOC104587090	LOC104596531	A0A1U7Z797	A0A1U7ZPF9	NAC transcription factor 29-like.	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.	0.772
LOC104587090	LOC104597915	A0A1U7Z797	A0A1U7ZW92	NAC transcription factor 29-like.	60S ribosomal protein L39.	0.807
LOC104587090	LOC104598979	A0A1U7Z797	A0A1U8ABX0	NAC transcription factor 29-like.	40S ribosomal protein S21-2-like isoform X1.	0.894
LOC104587090	LOC104600524	A0A1U7Z797	A0A1U8A5S9	NAC transcription factor 29-like.	40S ribosomal protein S29.	0.896
LOC104587090	LOC104601469	A0A1U7Z797	A0A1U8A8Y2	NAC transcription factor 29-like.	60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family.	0.807
LOC104587090	LOC104605100	A0A1U7Z797	A0A1U8AK03	NAC transcription factor 29-like.	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family.	0.814
LOC104587090	LOC104605292	A0A1U7Z797	A0A1U8ALS4	NAC transcription factor 29-like.	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.	0.772
LOC104587090	LOC104607638	A0A1U7Z797	A0A1U8AU69	NAC transcription factor 29-like.	ubiquitin-60S ribosomal protein L40.	0.879

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.679

expected number of edges:

20

PPI enrichment p-value:

0.000382

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006637

acyl-CoA metabolic process

8 of 17

2.25

5.75

2.01e-13

GO:0006084

acetyl-CoA metabolic process

6 of 10

2.36

4.74

2.20e-10

GO:0006085

acetyl-CoA biosynthetic process

5 of 6

2.5

4.31

4.12e-09

GO:0006086

acetyl-CoA biosynthetic process from pyruvate

4 of 4

2.58

3.51

2.22e-07

GO:0006099

Tricarboxylic acid cycle

5 of 20

1.98

3.0

2.63e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016624

Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

3 of 3

2.58

1.92

0.00029

GO:0016746

Acyltransferase activity

5 of 81

1.37

1.22

0.00072

GO:0004775

succinate-CoA ligase (ADP-forming) activity

2 of 2

2.58

1.1

0.0101

GO:0004739

Pyruvate dehydrogenase (acetyl-transferring) activity

2 of 2

2.58

1.1

0.0101

GO:0046912

Acyltransferase activity, acyl groups converted into alkyl on transfer

2 of 7

2.04

0.86

0.0241

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045239

Tricarboxylic acid cycle enzyme complex

5 of 6

2.5

4.18

7.58e-09

GO:0005967

Mitochondrial pyruvate dehydrogenase complex

4 of 4

2.58

3.37

4.21e-07

GO:1990204

Oxidoreductase complex

7 of 46

1.76

3.11

7.58e-09

GO:0042645

Mitochondrial nucleoid

4 of 10

2.18

2.79

2.56e-06

GO:0045252

Oxoglutarate dehydrogenase complex

3 of 3

2.58

2.53

1.90e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4979

Citrate cycle (TCA cycle)

10 of 14

2.44

8.96

1.26e-20

CL:4978

Citrate cycle (TCA cycle)

11 of 26

2.21

8.05

3.95e-21

CL:4981

Pyruvate dehydrogenase complex

5 of 5

2.58

4.67

9.86e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00020

Citrate cycle (TCA cycle)

11 of 27

2.19

8.14

8.88e-22

map01200

Carbon metabolism

10 of 90

1.63

3.7

2.63e-14

map00010

Glycolysis / Gluconeogenesis

5 of 36

1.72

2.44

1.02e-06

map00620

Pyruvate metabolism

5 of 41

1.67

2.31

1.48e-06

map00640

Propanoate metabolism

3 of 18

1.8

1.65

0.00033

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-71406

Pyruvate metabolism and Citric Acid (TCA) cycle

10 of 41

1.97

5.62

2.44e-16

MAP-389661

Glyoxylate metabolism and glycine degradation

7 of 19

2.15

4.85

1.29e-11

MAP-70268

Pyruvate metabolism

5 of 13

2.17

3.47

5.94e-08

MAP-71403

Citric acid cycle (TCA cycle)

6 of 26

1.95

3.43

1.11e-08

MAP-1428517

The citric acid (TCA) cycle and respiratory electron transport

10 of 105

1.56

3.24

7.02e-13

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990204

Oxidoreductase complex

7 of 37

1.86

3.47

2.17e-09

GOCC:0005967

Mitochondrial pyruvate dehydrogenase complex

4 of 4

2.58

3.26

7.22e-07

GOCC:0045239

Tricarboxylic acid cycle enzyme complex

4 of 8

2.28

2.85

2.54e-06

GOCC:0045252

Oxoglutarate dehydrogenase complex

3 of 4

2.46

2.2

7.59e-05

GOCC:1902494

Catalytic complex

8 of 525

0.76

0.63

0.00086

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0670

Pyruvate

3 of 9

2.1

1.66

0.00059

KW-0786

Thiamine pyrophosphate

2 of 5

2.18

1.01

0.0133

KW-0816

Tricarboxylic acid cycle

2 of 6

2.1

1.0

0.0133

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00549

CoA-ligase

3 of 3

2.58

2.07

0.00015

PF00364

Biotin-requiring enzyme

3 of 5

2.36

1.95

0.00021

PF02817

e3 binding domain

2 of 2

2.58

1.18

0.0070

PF00676

Dehydrogenase E1 component

2 of 2

2.58

1.18

0.0070

PF00285

Citrate synthase, C-terminal domain

2 of 2

2.58

1.18

0.0070

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016102

Succinyl-CoA synthetase-like

3 of 3

2.58

1.81

0.00047

IPR005811

ATP-citrate lyase/succinyl-CoA ligase

3 of 3

2.58

1.81

0.00047

IPR011053

Single hybrid motif

3 of 6

2.28

1.69

0.00065

IPR000089

Biotin/lipoyl attachment

3 of 6

2.28

1.69

0.00065

IPR029061

Thiamin diphosphate-binding fold

3 of 8

2.16

1.62

0.00077

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00861

Transketolase, pyrimidine binding domain

2 of 3

2.41

1.02

0.0135

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