STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC104594727DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (429 aa)    
Predicted Functional Partners:
LOC104597518
DNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family.
 
 0.978
LOC104588280
DNA-binding protein BIN4.
     
 0.707
LOC104608879
Crossover junction endonuclease MUS81 isoform X1.
    
 
 0.652
LOC104590525
DNA-binding protein RHL1 isoform X1.
  
 
 
 0.632
LOC104609450
DNA repair protein RAD50.
    
 0.626
LOC104613233
Meiotic recombination protein DMC1 homolog isoform X1; Belongs to the RecA family.
    
 0.618
LOC104600454
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination; Belongs to the RecA family. RAD51 subfamily.
    
 0.610
LOC104602252
DNA repair protein RAD51 homolog 3 isoform X1.
    
 0.599
LOC104599148
DNA repair protein XRCC3 homolog.
    
 0.589
LOC104587223
Serine/threonine-protein kinase ATM isoform X1; Belongs to the PI3/PI4-kinase family.
    
 0.550
Your Current Organism:
Nelumbo nucifera
NCBI taxonomy Id: 4432
Other names: Indian lotus, N. nucifera, Nelumbo nucifera Gaertn., padma, sacred lotus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.