node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC104585594 | LOC104591943 | A0A1U7YM10 | A0A1U7Z9Z8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Exonuclease 1 isoform X1. | 0.773 |
LOC104585594 | LOC104592513 | A0A1U7YM10 | A0A1U7ZQ25 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | formamidopyrimidine-DNA glycosylase isoform X1. | 0.695 |
LOC104585594 | LOC104598309 | A0A1U7YM10 | A0A1U8A1L0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein LOC104598309 isoform X1. | 0.660 |
LOC104585594 | LOC104604842 | A0A1U7YM10 | A0A1U8AJ26 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase I A, chloroplastic/mitochondrial. | 0.660 |
LOC104585594 | LOC104608879 | A0A1U7YM10 | A0A1U8Q9I0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Crossover junction endonuclease MUS81 isoform X1. | 0.843 |
LOC104585594 | LOC104608973 | A0A1U7YM10 | A0A1U8AYK8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Exonuclease 1 isoform X1. | 0.773 |
LOC104585594 | LOC104609450 | A0A1U7YM10 | A0A1U8B0E4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein RAD50. | 0.919 |
LOC104585594 | LOC104610895 | A0A1U7YM10 | A0A1U8B591 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase I A, chloroplastic/mitochondrial-like isoform X1. | 0.660 |
LOC104591943 | LOC104585594 | A0A1U7Z9Z8 | A0A1U7YM10 | Exonuclease 1 isoform X1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.773 |
LOC104591943 | LOC104592513 | A0A1U7Z9Z8 | A0A1U7ZQ25 | Exonuclease 1 isoform X1. | formamidopyrimidine-DNA glycosylase isoform X1. | 0.695 |
LOC104591943 | LOC104598309 | A0A1U7Z9Z8 | A0A1U8A1L0 | Exonuclease 1 isoform X1. | Uncharacterized protein LOC104598309 isoform X1. | 0.675 |
LOC104591943 | LOC104604842 | A0A1U7Z9Z8 | A0A1U8AJ26 | Exonuclease 1 isoform X1. | DNA polymerase I A, chloroplastic/mitochondrial. | 0.675 |
LOC104591943 | LOC104608746 | A0A1U7Z9Z8 | A0A1U8B1Q3 | Exonuclease 1 isoform X1. | Flap endonuclease GEN-like 2. | 0.773 |
LOC104591943 | LOC104608879 | A0A1U7Z9Z8 | A0A1U8Q9I0 | Exonuclease 1 isoform X1. | Crossover junction endonuclease MUS81 isoform X1. | 0.892 |
LOC104591943 | LOC104608973 | A0A1U7Z9Z8 | A0A1U8AYK8 | Exonuclease 1 isoform X1. | Exonuclease 1 isoform X1. | 0.908 |
LOC104591943 | LOC104609450 | A0A1U7Z9Z8 | A0A1U8B0E4 | Exonuclease 1 isoform X1. | DNA repair protein RAD50. | 0.919 |
LOC104591943 | LOC104610895 | A0A1U7Z9Z8 | A0A1U8B591 | Exonuclease 1 isoform X1. | DNA polymerase I A, chloroplastic/mitochondrial-like isoform X1. | 0.675 |
LOC104591943 | LOC104612691 | A0A1U7Z9Z8 | A0A1U8BB72 | Exonuclease 1 isoform X1. | Flap endonuclease GEN-like 1. | 0.773 |
LOC104592513 | LOC104585594 | A0A1U7ZQ25 | A0A1U7YM10 | formamidopyrimidine-DNA glycosylase isoform X1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.695 |
LOC104592513 | LOC104591943 | A0A1U7ZQ25 | A0A1U7Z9Z8 | formamidopyrimidine-DNA glycosylase isoform X1. | Exonuclease 1 isoform X1. | 0.695 |