LOC104611724 protein (Nelumbo nucifera) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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gene co-occurrence

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Score

LOC104611724

Putative RNA methyltransferase At5g10620. (187 aa)

Predicted Functional Partners:

LOC104591650

0.959

LOC104601951

0.823

LOC104594258

0.779

LOC104595599

0.634

LOC104605419

0.631

LOC104588556

0.601

LOC104595595

0.601

LOC104593820

0.591

LOC104608906

0.581

LOC104603453

0.577

Your Current Organism:

Nelumbo nucifera

NCBI taxonomy Id: 4432
Other names: Indian lotus, N. nucifera, Nelumbo nucifera Gaertn., padma, sacred lotus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC104588556	LOC104593820	A0A1U7YWH0	A0A1U7ZKE8	Threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1.	Uncharacterized protein LOC104593820 isoform X1.	0.586
LOC104588556	LOC104595599	A0A1U7YWH0	A0A1U7ZZK5	Threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1.	Uncharacterized protein LOC104595599 isoform X1.	0.577
LOC104588556	LOC104605419	A0A1U7YWH0	A0A1U8AL64	Threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1.	Uncharacterized protein LOC104605419.	0.521
LOC104588556	LOC104608906	A0A1U7YWH0	A0A1U8BAB4	Threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1.	Uncharacterized protein LOC104608906 isoform X1.	0.628
LOC104588556	LOC104611724	A0A1U7YWH0	A0A1U8BK55	Threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1.	Putative RNA methyltransferase At5g10620.	0.601
LOC104591650	LOC104594258	A0A1U7ZKJ8	A0A1U7ZGA8	Protein Iojap-related, mitochondrial.	Nicotinamide-nucleotide adenylyltransferase.	0.918
LOC104591650	LOC104601951	A0A1U7ZKJ8	A0A1U8AMT9	Protein Iojap-related, mitochondrial.	Delta-1-pyrroline-5-carboxylate synthase; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family.	0.828
LOC104591650	LOC104611724	A0A1U7ZKJ8	A0A1U8BK55	Protein Iojap-related, mitochondrial.	Putative RNA methyltransferase At5g10620.	0.959
LOC104593820	LOC104588556	A0A1U7ZKE8	A0A1U7YWH0	Uncharacterized protein LOC104593820 isoform X1.	Threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1.	0.586
LOC104593820	LOC104595595	A0A1U7ZKE8	A0A1U7ZZK1	Uncharacterized protein LOC104593820 isoform X1.	CDK5RAP1-like protein.	0.586
LOC104593820	LOC104595599	A0A1U7ZKE8	A0A1U7ZZK5	Uncharacterized protein LOC104593820 isoform X1.	Uncharacterized protein LOC104595599 isoform X1.	0.585
LOC104593820	LOC104601951	A0A1U7ZKE8	A0A1U8AMT9	Uncharacterized protein LOC104593820 isoform X1.	Delta-1-pyrroline-5-carboxylate synthase; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family.	0.788
LOC104593820	LOC104603453	A0A1U7ZKE8	A0A1U8ASJ3	Uncharacterized protein LOC104593820 isoform X1.	Uncharacterized protein LOC104603453.	0.613
LOC104593820	LOC104605419	A0A1U7ZKE8	A0A1U8AL64	Uncharacterized protein LOC104593820 isoform X1.	Uncharacterized protein LOC104605419.	0.890
LOC104593820	LOC104608906	A0A1U7ZKE8	A0A1U8BAB4	Uncharacterized protein LOC104593820 isoform X1.	Uncharacterized protein LOC104608906 isoform X1.	0.641
LOC104593820	LOC104611724	A0A1U7ZKE8	A0A1U8BK55	Uncharacterized protein LOC104593820 isoform X1.	Putative RNA methyltransferase At5g10620.	0.591
LOC104594258	LOC104591650	A0A1U7ZGA8	A0A1U7ZKJ8	Nicotinamide-nucleotide adenylyltransferase.	Protein Iojap-related, mitochondrial.	0.918
LOC104594258	LOC104595599	A0A1U7ZGA8	A0A1U7ZZK5	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein LOC104595599 isoform X1.	0.405
LOC104594258	LOC104601951	A0A1U7ZGA8	A0A1U8AMT9	Nicotinamide-nucleotide adenylyltransferase.	Delta-1-pyrroline-5-carboxylate synthase; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family.	0.878
LOC104594258	LOC104603453	A0A1U7ZGA8	A0A1U8ASJ3	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein LOC104603453.	0.498

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

42

PPI enrichment p-value:

0.00898

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070646

Protein modification by small protein removal

10 of 111

2.32

8.05

2.37e-19

GO:0016579

Protein deubiquitination

9 of 92

2.36

7.48

2.49e-17

GO:0070647

Protein modification by small protein conjugation or removal

11 of 649

1.59

3.63

5.84e-15

GO:0006511

Ubiquitin-dependent protein catabolic process

7 of 420

1.59

2.47

8.59e-08

GO:0006508

Proteolysis

11 of 1175

1.34

2.35

2.87e-12

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0101005

Deubiquitinase activity

10 of 92

2.4

8.79

1.57e-20

GO:0004843

Cysteine-type deubiquitinase activity

8 of 81

2.36

6.79

1.88e-15

GO:0140492

Metal-dependent deubiquitinase activity

3 of 13

2.73

9.09e-06

GO:0140096

Catalytic activity, acting on a protein

11 of 2327

1.04

1.36

1.35e-09

GO:0004197

Cysteine-type endopeptidase activity

3 of 106

1.82

1.27

0.0027

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5688426

Deubiquitination

7 of 282

1.76

3.08

9.24e-09

MAP-5689880

Ub-specific processing proteases

4 of 193

1.68

1.56

0.00036

MAP-597592

Post-translational protein modification

8 of 1707

1.04

1.06

3.68e-05

MAP-5689901

Metalloprotease DUBs

2 of 24

2.29

1.0

0.0144

MAP-392499

Metabolism of proteins

8 of 2233

0.92

0.84

0.00020

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0833

Ubl conjugation pathway

3 of 88

1.9

1.35

0.0020

KW-0788

Thiol protease

2 of 38

2.09

0.93

0.0183

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13423

Ubiquitin carboxyl-terminal hydrolase

5 of 28

2.62

4.54

2.05e-09

PF02338

OTU-like cysteine protease

2 of 13

2.55

1.0

0.0150

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038765

Papain-like cysteine peptidase superfamily

7 of 134

2.08

4.28

2.16e-10

IPR001394

Peptidase C19, ubiquitin carboxyl-terminal hydrolase

5 of 37

2.5

4.11

1.07e-08

IPR028889

Ubiquitin specific protease domain

5 of 40

2.46

4.08

1.07e-08

IPR018200

Ubiquitin specific protease, conserved site

4 of 32

2.46

3.07

1.35e-06

IPR037518

MPN domain

3 of 13

2.73

2.43

3.30e-05

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00232

JAB/MPN domain

3 of 12

2.76

2.6

1.64e-05

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