STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPSG_020432-oxoisovalerate dehydrogenase subunit beta. (388 aa)    
Predicted Functional Partners:
CPSG_01827
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
CPSG_00306
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.993
CPSG_01534
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.988
CPSG_05815
Dihydrolipoyl dehydrogenase.
  
 0.978
CPSG_05915
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.961
CPSG_00001
Dihydrolipoamide S-succinyltransferase.
 
 0.959
CPSG_04302
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.953
CPSG_08930
Pyruvate dehydrogenase complex component Pdx1.
  
 0.939
CPSG_02839
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.896
CPSG_07298
3-methylcrotonyl-CoA carboxylase subunit alpha.
  
 0.889
Your Current Organism:
Coccidioides posadasii
NCBI taxonomy Id: 443226
Other names: C. posadasii str. Silveira, Coccidioides posadasii str. Silveira
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.