STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPSG_02381Tubulin-tyrosine ligase. (742 aa)    
Predicted Functional Partners:
CPSG_00935
Decapping enzyme Dcp1.
    
 
 0.924
CPSG_03921
YjeF_N domain-containing protein.
    
 
 0.804
CPSG_09472
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
    
 
 0.804
CPSG_03871
mRNA-decapping enzyme subunit 2.
    
 
 0.800
CPSG_07643
Uncharacterized protein.
    
 
 0.800
CPSG_02380
Uncharacterized protein.
 
      0.753
CPSG_00142
AMP deaminase.
     
 0.751
CPSG_06336
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
     
 0.744
CPSG_01755
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
    
 0.736
CPSG_01369
GDA1/CD39 nucleoside phosphatase; Belongs to the GDA1/CD39 NTPase family.
     
 0.706
Your Current Organism:
Coccidioides posadasii
NCBI taxonomy Id: 443226
Other names: C. posadasii str. Silveira, Coccidioides posadasii str. Silveira
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.