STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPSG_06820Cell cycle protein kinase. (486 aa)    
Predicted Functional Partners:
CPSG_02013
DBF4-type domain-containing protein.
   
 0.999
CPSG_09920
DNA helicase; Belongs to the MCM family.
   
 0.996
CPSG_02196
DNA helicase; Belongs to the MCM family.
   
 0.995
CPSG_00608
DNA helicase; Belongs to the MCM family.
   
 0.993
CPSG_07934
DNA helicase; Belongs to the MCM family.
   
 0.991
CPSG_08524
DNA helicase; Belongs to the MCM family.
   
 0.991
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
 0.988
CPSG_01738
Protein kinase.
    
 
 0.987
CPSG_02373
Zf-primase domain-containing protein.
   
 0.982
CPSG_08191
Uncharacterized protein.
    
 0.964
Your Current Organism:
Coccidioides posadasii
NCBI taxonomy Id: 443226
Other names: C. posadasii str. Silveira, Coccidioides posadasii str. Silveira
Server load: low (10%) [HD]