STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEX84674.1Hypothetical protein. (1396 aa)    
Predicted Functional Partners:
AEX84673.1
PFAM: Uncharacterized protein conserved in bacteria C-term(DUF2220).
 
     0.950
AEX84592.1
Hypothetical protein.
  
 
 0.796
AEX84671.1
Hypothetical protein.
       0.788
AEX84672.1
Hypothetical protein.
       0.788
AEX84675.1
Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; TIGRFAM: intein N-terminal splicing region.
     
 0.621
AEX84677.1
PFAM: Domain of unknown function (DUF1987).
 
     0.614
AEX84678.1
Hypothetical protein.
 
     0.609
AEX84676.1
PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box.
     
 0.578
gyrB
Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA stran [...]
   
 
 0.553
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.522
Your Current Organism:
Marinitoga piezophila
NCBI taxonomy Id: 443254
Other names: M. piezophila KA3, Marinitoga piezophila KA3, Marinitoga piezophila str. KA3, Marinitoga piezophila strain KA3, Thermotogales sp. KA3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.