STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEX84696.1Hypothetical protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. (81 aa)    
Predicted Functional Partners:
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.795
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.674
nadD
Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.571
obg
Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.556
AEX84699.1
PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase.
       0.549
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.530
AEX85944.1
TIGR00255 family protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein.
  
    0.516
AEX84700.1
Putative SAM-dependent methyltransferase; PFAM: S-adenosylmethionine-dependent methyltransferase.
       0.462
AEX85826.1
Fe-S oxidoreductase; PFAM: Radical SAM superfamily; B12 binding domain.
  
     0.441
AEX84693.1
Xaa-Pro aminopeptidase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family.
  
    0.425
Your Current Organism:
Marinitoga piezophila
NCBI taxonomy Id: 443254
Other names: M. piezophila KA3, Marinitoga piezophila KA3, Marinitoga piezophila str. KA3, Marinitoga piezophila strain KA3, Thermotogales sp. KA3
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.