STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEX84756.1PFAM: DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; manually curated. (424 aa)    
Predicted Functional Partners:
AEX86270.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
  
 
0.913
dnaG
DNA primase, catalytic core; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 0.896
AEX84757.1
PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
 
 
 0.893
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.835
AEX84754.1
PFAM: Conserved phage C-terminus (Phg_2220_C); TIGRFAM: phage conserved hypothetical protein, C-terminal domain.
  
  
 0.826
AEX84758.1
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
  
 0.815
AEX84761.1
Holliday junction resolvase; PFAM: Endodeoxyribonuclease RusA.
     
 0.791
AEX84755.1
Hypothetical protein.
       0.773
AEX84759.1
Hypothetical protein.
       0.773
AEX84760.1
Hypothetical protein.
       0.773
Your Current Organism:
Marinitoga piezophila
NCBI taxonomy Id: 443254
Other names: M. piezophila KA3, Marinitoga piezophila KA3, Marinitoga piezophila str. KA3, Marinitoga piezophila strain KA3, Thermotogales sp. KA3
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