STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEX86334.1Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (311 aa)    
Predicted Functional Partners:
AEX86333.1
DRTGG domain-containing protein; PFAM: DRTGG domain.
 
     0.955
AEX86337.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
  
 0.954
AEX86335.1
DRTGG domain-containing protein; PFAM: DRTGG domain.
 
     0.952
AEX86336.1
Putative metal-dependent phosphoesterase, PHP family; PFAM: PHP domain.
 
     0.952
AEX86166.1
PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.914
AEX85187.1
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
 
 0.899
AEX85407.1
PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.899
AEX86160.1
PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.899
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.832
AEX86330.1
Putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon; PFAM: Protein of unknown function (DUF342).
 
     0.821
Your Current Organism:
Marinitoga piezophila
NCBI taxonomy Id: 443254
Other names: M. piezophila KA3, Marinitoga piezophila KA3, Marinitoga piezophila str. KA3, Marinitoga piezophila strain KA3, Thermotogales sp. KA3
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.