node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KKB08526.1 | KKB10529.1 | VE25_18625 | VE25_17480 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.425 |
KKB08526.1 | KKB10570.1 | VE25_18625 | VE25_17720 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.573 |
KKB08526.1 | KKB10598.1 | VE25_18625 | VE25_17130 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.877 |
KKB08526.1 | KKB10599.1 | VE25_18625 | VE25_17135 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. | 0.948 |
KKB08526.1 | KKB11903.1 | VE25_18625 | VE25_10140 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.815 |
KKB10529.1 | KKB08526.1 | VE25_17480 | VE25_18625 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.425 |
KKB10529.1 | KKB10598.1 | VE25_17480 | VE25_17130 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.541 |
KKB10529.1 | KKB11903.1 | VE25_17480 | VE25_10140 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
KKB10529.1 | KKB13063.1 | VE25_17480 | VE25_03985 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.969 |
KKB10570.1 | KKB08526.1 | VE25_17720 | VE25_18625 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.573 |
KKB10570.1 | KKB10598.1 | VE25_17720 | VE25_17130 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | 0.535 |
KKB10598.1 | KKB08526.1 | VE25_17130 | VE25_18625 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.877 |
KKB10598.1 | KKB10529.1 | VE25_17130 | VE25_17480 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.541 |
KKB10598.1 | KKB10570.1 | VE25_17130 | VE25_17720 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.535 |
KKB10598.1 | KKB10599.1 | VE25_17130 | VE25_17135 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. | 0.687 |
KKB10598.1 | KKB10701.1 | VE25_17130 | VE25_16620 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.705 |
KKB10598.1 | KKB10702.1 | VE25_17130 | VE25_16625 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
KKB10598.1 | KKB11509.1 | VE25_17130 | VE25_12460 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Nitrogen regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.809 |
KKB10598.1 | KKB11903.1 | VE25_17130 | VE25_10140 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.667 |
KKB10598.1 | KKB13063.1 | VE25_17130 | VE25_03985 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.898 |