STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP2BDNA topoisomerase II beta. (1621 aa)    
Predicted Functional Partners:
SMC2
Structural maintenance of chromosomes 2.
   
 
 0.897
SPO11
SPO11 initiator of meiotic double stranded breaks.
    
 0.862
CDK1
Cyclin dependent kinase 1.
   
 0.831
TOP1
DNA topoisomerase I.
   
 
 0.820
TOP1MT
DNA topoisomerase I mitochondrial.
   
 
 0.815
LOC102074082
Structural maintenance of chromosomes protein 4.
   
 
 0.813
KCTD9
Potassium channel tetramerization domain containing 9.
   
 
 0.808
SMC6
Structural maintenance of chromosomes 6.
   
 
 0.808
UBE2C
Ubiquitin conjugating enzyme E2 C.
   
 0.802
CDC20
Cell division cycle 20.
  
 
 0.783
Your Current Organism:
Zonotrichia albicollis
NCBI taxonomy Id: 44394
Other names: Z. albicollis, white-throated sparrow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.