STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tneu_0610TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); KEGG: pis:Pisl_1579 sugar isomerase (SIS). (202 aa)    
Predicted Functional Partners:
Tneu_0708
PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: pis:Pisl_1686 orotidine 5'-phosphate decarboxylase.
 
 0.999
Tneu_0669
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: sugar isomerase (SIS); KEGG: pis:Pisl_1645 bifunctional phosphoglucose/phosphomannose isomerase.
    
 0.941
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
  0.900
Tneu_0789
PFAM: Transketolase central region; Transketolase domain protein; KEGG: pis:Pisl_1775 transketolase, central region.
    
  0.900
Tneu_0790
PFAM: Transketolase domain protein; KEGG: pis:Pisl_1776 transketolase domain protein.
    
  0.900
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
       0.718
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.635
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.591
Tneu_0070
PFAM: PfkB domain protein; KEGG: pis:Pisl_1117 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
  
    0.492
Tneu_1554
PFAM: PfkB domain protein; KEGG: pis:Pisl_0564 PfkB domain protein.
  
    0.492
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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