STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (892 aa)    
Predicted Functional Partners:
Tneu_1159
SMART: WD-40 repeat protein.
  
 0.932
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: pis:Pisl_1246 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.859
Tneu_1456
aminoacyl-tRNA synthetase class Ia; KEGG: pis:Pisl_1019 valyl-tRNA synthetase.
 
  
 0.858
nac
Ubiquitin-associated- domain-containing protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.835
Tneu_0677
TIGRFAM: isoleucyl-tRNA synthetase; KEGG: pis:Pisl_1650 isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.813
htpX
PFAM: peptidase M48 Ste24p; KEGG: pis:Pisl_0989 peptidase M48, Ste24p; Belongs to the peptidase M48B family.
  
    0.789
thrS
Threonyl-tRNA synthetase editing domain protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.764
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.758
Tneu_0312
KEGG: pis:Pisl_1364 hypothetical protein.
  
    0.757
rpl10e
PFAM: ribosomal protein L16; KEGG: pas:Pars_2226 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
  
  
 0.728
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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