Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tneu_1027Methyltransferase small; PFAM: putative RNA methylase; methyltransferase small; KEGG: pis:Pisl_0747 methyltransferase small. (202 aa)    
Predicted Functional Partners:
pus10
THUMP domain protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
     0.616
Tneu_1734
KEGG: pai:PAE2994 hypothetical protein.
 
     0.611
Tneu_0819
KEGG: pas:Pars_2053 DNA-directed RNA polymerase subunit L.
  
    0.584
Tneu_1026
KEGG: pis:Pisl_0746 hypothetical protein.
       0.559
csl4
Conserved protein (RNA polymerase related); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
       0.549
Tneu_0160
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: pis:Pisl_1222 metal dependent phosphohydrolase.
   
    0.542
rpl10e
PFAM: ribosomal protein L16; KEGG: pas:Pars_2226 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
  
    0.536
Tneu_1681
KEGG: pas:Pars_1789 transcription termination factor Tfs; TIGRFAM: transcription factor S; PFAM: Transcription factor TFIIS; SMART: DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
 
    0.498
Tneu_1931
PFAM: Protein of unknown function DUF371; KEGG: pcl:Pcal_2061 protein of unknown function DUF371.
   
    0.440
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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