Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Tneu_1111PFAM: Methyltransferase type 11; KEGG: tfu:Tfu_2465 hypothetical protein. (367 aa)    
Predicted Functional Partners:
Tneu_1112
PFAM: Methyltransferase type 11.
       0.773
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
    
 0.565
Tneu_1110
PFAM: phosphoadenosine phosphosulfate reductase; KEGG: tac:Ta1396 hypothetical protein.
       0.551
Tneu_1159
SMART: WD-40 repeat protein.
  
 0.429
Tneu_1788
PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: pis:Pisl_0335 NADH dehydrogenase (ubiquinone), 30 kDa subunit.
  
 0.411
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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