STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tneu_1182PFAM: protein of unknown function DUF81; KEGG: pis:Pisl_1910 protein of unknown function DUF81. (283 aa)    
Predicted Functional Partners:
Tneu_1183
PFAM: protein of unknown function DUF1634; KEGG: pis:Pisl_1909 protein of unknown function DUF1634.
 
  
 0.933
Tneu_1184
PFAM: protein of unknown function UPF0066; KEGG: pis:Pisl_1908 protein of unknown function UPF0066.
     
 0.782
Tneu_1185
KEGG: pai:PAE2455 30S ribosomal protein S30e.
       0.668
Tneu_1186
PFAM: protein of unknown function DUF401; KEGG: pis:Pisl_1905 protein of unknown function DUF401.
       0.668
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.664
tdk
PFAM: thymidine kinase; KEGG: pas:Pars_1427 thymidine kinase.
       0.629
Tneu_1181
PFAM: Citrate transporter; KEGG: pis:Pisl_1911 citrate transporter.
  
  
 0.612
Tneu_1879
PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; KEGG: pis:Pisl_1412 peptidase S1 and S6, chymotrypsin/Hap.
   
 
 0.555
Tneu_2001
TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein; KEGG: pis:Pisl_0649 MoaD family protein.
       0.533
Tneu_1188
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pis:Pisl_1904 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
       0.503
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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