STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tneu_1259PFAM: extracellular solute-binding protein family 3; KEGG: pis:Pisl_1863 extracellular solute-binding protein, family 3. (295 aa)    
Predicted Functional Partners:
Tneu_1298
TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pis:Pisl_1820 polar amino acid ABC transporter, inner membrane subunit.
 
 0.990
Tneu_1297
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pis:Pisl_1821 ABC transporter related.
 
 
 0.895
rps14
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
  
    0.701
Tneu_1260
PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pis:Pisl_1862 FAD dependent oxidoreductase.
  
  
 0.598
Tneu_0978
PFAM: periplasmic binding protein; KEGG: pis:Pisl_0059 periplasmic binding protein.
  
  
 0.556
argH
PFAM: fumarate lyase; KEGG: pis:Pisl_0281 argininosuccinate lyase.
  
  
 0.498
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
  
  
 0.494
argG
PFAM: argininosuccinate synthase; KEGG: pis:Pisl_0279 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.486
Tneu_0539
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pis:Pisl_1436 butyryl-CoA dehydrogenase.
  
  
 0.415
Tneu_1268
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pis:Pisl_1853 acyl-CoA dehydrogenase domain protein.
  
  
 0.415
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.