STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tneu_1338TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: pis:Pisl_0947 MoaD family protein. (100 aa)    
Predicted Functional Partners:
Tneu_2001
TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein; KEGG: pis:Pisl_0649 MoaD family protein.
 
 0.995
Tneu_0187
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pis:Pisl_1261 UBA/ThiF-type NAD/FAD binding protein.
 
 0.980
Tneu_1291
PFAM: thiamineS protein; KEGG: pis:Pisl_1827 hypothetical protein.
  
  
  0.918
Tneu_1240
PFAM: thiamineS protein; KEGG: pas:Pars_1003 MoaD family protein.
  
  
 
0.907
Tneu_0046
PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: pis:Pisl_1091 molybdenum cofactor biosynthesis protein (MoaC).
  
  
 0.820
Tneu_1339
KEGG: pis:Pisl_0946 hypothetical protein.
       0.749
Tneu_0185
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pis:Pisl_1238 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.674
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
  
 0.631
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.573
Tneu_0519
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pis:Pisl_1463 radical SAM domain protein.
  
  
 0.558
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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