STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tneu_1356TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: pis:Pisl_0811 hypothetical protein; Belongs to the thiolase-like superfamily. UPF0219 family. (351 aa)    
Predicted Functional Partners:
Tneu_1357
PFAM: protein of unknown function DUF35; KEGG: pai:PAE2184 conserved protein associated with acetyl-CoA C-acyltransferase.
 
 
 0.999
Tneu_1358
KEGG: pis:Pisl_0813 acetyl-CoA C-acyltransferase.
 
 0.999
Tneu_1359
KEGG: pcl:Pcal_1085 3-hydroxy-3-methylglutaryl coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 
 0.999
Tneu_0249
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: pis:Pisl_1301 acetyl-CoA acetyltransferase.
  
 0.997
Tneu_0176
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pai:PAE1040 pyruvate ferredoxin oxidoreductase gamma subunit (PorG).
    
 0.910
Tneu_1529
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pai:PAE3279 2-ketoacid ferredoxin oxidoreductase gamma subunit.
    
 0.910
Tneu_0130
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: pis:Pisl_1174 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.900
Tneu_0131
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pis:Pisl_1175 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
  0.900
Tneu_0177
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pis:Pisl_1231 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit.
     
  0.900
Tneu_0178
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pas:Pars_0195 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
  0.900
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.