node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tneu_0001 | Tneu_0104 | Tneu_0001 | Tneu_0104 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | 0.997 |
Tneu_0001 | Tneu_0905 | Tneu_0001 | Tneu_0905 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | KEGG: pas:Pars_0255 DNA polymerase B region. | 0.836 |
Tneu_0001 | Tneu_1320 | Tneu_0001 | Tneu_1320 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | KEGG: pis:Pisl_0961 DNA polymerase II; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.810 |
Tneu_0001 | Tneu_1361 | Tneu_0001 | Tneu_1361 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pis:Pisl_0816 DNA polymerase I. | 0.854 |
Tneu_0001 | fen | Tneu_0001 | Tneu_1985 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | XPG I domain protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] | 0.738 |
Tneu_0001 | pcn | Tneu_0001 | Tneu_1682 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.500 |
Tneu_0001 | pcn-2 | Tneu_0001 | Tneu_1995 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.677 |
Tneu_0001 | priL | Tneu_0001 | Tneu_1401 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.967 |
Tneu_0001 | priS | Tneu_0001 | Tneu_1683 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.923 |
Tneu_0001 | rfcL | Tneu_0001 | Tneu_2009 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | AAA ATPase central domain protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.450 |
Tneu_0104 | Tneu_0001 | Tneu_0104 | Tneu_0001 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. | 0.997 |
Tneu_0104 | Tneu_0905 | Tneu_0104 | Tneu_0905 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | KEGG: pas:Pars_0255 DNA polymerase B region. | 0.956 |
Tneu_0104 | Tneu_1320 | Tneu_0104 | Tneu_1320 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | KEGG: pis:Pisl_0961 DNA polymerase II; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. | 0.966 |
Tneu_0104 | Tneu_1361 | Tneu_0104 | Tneu_1361 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pis:Pisl_0816 DNA polymerase I. | 0.965 |
Tneu_0104 | fen | Tneu_0104 | Tneu_1985 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | XPG I domain protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] | 0.856 |
Tneu_0104 | pcn | Tneu_0104 | Tneu_1682 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.859 |
Tneu_0104 | pcn-2 | Tneu_0104 | Tneu_1995 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.821 |
Tneu_0104 | priL | Tneu_0104 | Tneu_1401 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.963 |
Tneu_0104 | priS | Tneu_0104 | Tneu_1683 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.925 |
Tneu_0104 | rfcL | Tneu_0104 | Tneu_2009 | MCM family protein; PFAM: magnesium chelatase ChlI subunit; MCM family protein; ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pis:Pisl_1152 MCM family protein; Belongs to the MCM family. | AAA ATPase central domain protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.852 |