STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmSGlucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (600 aa)    
Predicted Functional Partners:
Tneu_0456
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: pis:Pisl_0144 glutamate--ammonia ligase.
 
 
 0.964
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pis:Pisl_1184 carbamoyl phosphate synthase large subunit; Belongs to the CarB family.
   
 0.956
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
 0.942
Tneu_0669
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: sugar isomerase (SIS); KEGG: pis:Pisl_1645 bifunctional phosphoglucose/phosphomannose isomerase.
  
 
 0.939
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: pis:Pisl_1183 carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
    
 0.934
Tneu_1904
Amidophosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: pis:Pisl_0109 amidophosphoribosyltransferase.
   
 0.926
Tneu_1911
Amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; phosphoribosyltransferase; KEGG: pis:Pisl_0102 amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.926
Tneu_1728
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pis:Pisl_0400 putative glutamate synthase subunit beta.
    
 0.925
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.884
Tneu_1694
KEGG: pis:Pisl_0427 nucleotidyl transferase.
 
   
 0.870
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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