STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABX01731.1Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: AAA ATPase; KEGG: mvn:Mevan_1030 regulatory protein ArsR. (408 aa)    
Predicted Functional Partners:
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
     
 0.895
ABX01729.1
Protein of unknown function DUF201; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: mvn:Mevan_1032 protein of unknown function DUF201.
 
     0.870
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
     
 0.814
ABX01727.1
KEGG: mvn:Mevan_1034 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
       0.792
ABX01726.1
PFAM: type II secretion system protein; KEGG: mvn:Mevan_1035 type II secretion system protein.
  
     0.736
flaK
Peptidase A24B, FlaK domain protein; Cleaves the N-terminal leader peptide from preflagellins.
 
   
 0.711
ABX02228.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mvn:Mevan_0571 porphobilinogen synthase; Belongs to the ALAD family.
     
 0.693
ABX01852.1
PFAM: SirA family protein; DsrE family protein; KEGG: mae:Maeo_0501 DsrE family protein.
 
   
 0.669
ABX02062.1
PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: mvn:Mevan_0735 oligosaccharyl transferase STT3 subunit.
  
     0.655
ABX02362.1
PFAM: protein of unknown function UPF0153; KEGG: mvn:Mevan_0442 protein of unknown function UPF0153.
 
   
 0.655
Your Current Organism:
Methanococcus maripaludis C6
NCBI taxonomy Id: 444158
Other names: M. maripaludis C6, Methanococcus maripaludis str. C6, Methanococcus maripaludis strain C6
Server load: low (14%) [HD]