STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaNDNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA.
  
 0.999
ABS30522.1
Putative DNA polymerase III, alpha subunit (dnaE)/DNA polymerase III, epsilon subunit (dnaQ) fusion; Predicted based on similarity to TIGRFAM TIGR00594 and TIGR01406, Pfam PF00929, and related proteins in nr [COG0587, COG0847; L].
 
 0.999
mutL
Putative DNA mismatch repair protein MutL; Predicted based on similarity to TIGRFAM TIGR00585, Pfam PF01119, and related proteins in nr [COG0323; L]; Belongs to the DNA mismatch repair MutL/HexB family.
  
 0.999
pheT
phenylalanyl-tRNA synthetase beta subunit; Predicted based on similarity to Pfam PF03483, PF03484 and related proteins in nr [COG0072; J]; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.972
gyrA
Type IV DNA gyrase A subunit; Predicted based on similarity to Pfam PF00521 and related proteins in nr [COG0188; L].
  
  
 0.831
ftsH
Putative ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
       0.791
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
     
 0.779
gyrB
DNA gyrase B subunit; Predicted based on similarity to Pfam PF00986, PF00204 and related proteins in nr [COG0187; L].
  
 
 0.767
ABS30441.1
Putative methyltransferase; Predicted based on similarity to Pfam PF03602 and related proteins in nr.
 
     0.687
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
    0.684
Your Current Organism:
Sulcia muelleri GWSS
NCBI taxonomy Id: 444179
Other names: C. Sulcia muelleri GWSS, Candidatus Sulcia muelleri GWSS, Candidatus Sulcia muelleri str. GWSS, Candidatus Sulcia muelleri strain GWSS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.