STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
gidAGlucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (611 aa)    
Predicted Functional Partners:
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.996
gidB
Glucose-inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.933
ybeY
Conserved hypothetical protein SMGWSS_025; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.883
glnS
glutaminyl-tRNA synthetase; Predicted based on similarity to TIGRFAM equivalog TIGR00440 [COG0008; J].
  
  
 0.835
ABS30522.1
Putative DNA polymerase III, alpha subunit (dnaE)/DNA polymerase III, epsilon subunit (dnaQ) fusion; Predicted based on similarity to TIGRFAM TIGR00594 and TIGR01406, Pfam PF00929, and related proteins in nr [COG0587, COG0847; L].
     
 0.766
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
 
 0.656
rsmI
S-adenosyl-L-methionine dependent methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
     
 0.617
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
  
 0.611
rpmH
50S ribosomal subunit protein L34; Predicted based on similarity to TIGRFAM equivalog TIGR01030 [COG0230; J]; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.567
gyrB
DNA gyrase B subunit; Predicted based on similarity to Pfam PF00986, PF00204 and related proteins in nr [COG0187; L].
  
  
 0.559
Your Current Organism:
Sulcia muelleri GWSS
NCBI taxonomy Id: 444179
Other names: C. Sulcia muelleri GWSS, Candidatus Sulcia muelleri GWSS, Candidatus Sulcia muelleri str. GWSS, Candidatus Sulcia muelleri strain GWSS
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