STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceFDihydrolipoamide acyltransferase E2 component; Predicted based on similarity to Pfam PF00198 and related proteins in nr [COG0508; C]. (371 aa)    
Predicted Functional Partners:
lpdA
Dihydrolipoamide dehydrogenase; Predicted based on similarity to COG COG1249 and related proteins in nr [COG1249; C].
 
 0.999
acoB
Putative pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
acoA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
lpdA-2
Dihydrolipoamide dehydrogenase; Predicted based on similarity to COG COG1249 and related proteins in nr [COG1249; C].
 
 0.998
sucA
2-oxoglutarate dehydrogenase, E1 component; Predicted based on similarity to TIGRFAM equivalog TIGR00239 [COG0567; C].
 
 0.995
prsA
Ribose-phosphate pyrophosphokinase; Predicted based on similarity to TIGRFAM TIGR01251 and related proteins in nr [COG0462; F].
   
 0.986
korA
Putative 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; Predicted based on similarity to Pfam PF01855 and related proteins in nr [COG0674; C].
     
 0.957
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.951
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.934
korB
2-oxoglutarate ferredoxin oxidoreductase beta subunit; Predicted based on similarity to related proteins in nr [COG1013; C].
   
 
 0.910
Your Current Organism:
Sulcia muelleri GWSS
NCBI taxonomy Id: 444179
Other names: C. Sulcia muelleri GWSS, Candidatus Sulcia muelleri GWSS, Candidatus Sulcia muelleri str. GWSS, Candidatus Sulcia muelleri strain GWSS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.