Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
lipARadical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (334 aa)    
Predicted Functional Partners:
gcvH
Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.957
ALE78053.1
Protochlorophyllide oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.784
ALE78049.1
Dihydrolipoamide acetyltransferase.
 
 
 0.765
ALE78516.1
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 
 0.701
ALE79681.1
Hypothetical protein.
 
 
 0.685
ALE78055.1
Membrane protein.
       0.679
ALE79300.1
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 
  
 0.654
ALE78048.1
Dihydrolipoamide dehydrogenase.
 
  
 0.640
ALE78993.1
Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity.
 
  
 0.592
ALE78052.1
F420-dependent oxidoreductase.
       0.572
Your Current Organism:
Pseudonocardia sp. AL04100510
NCBI taxonomy Id: 445576
Other names: P. sp. AL041005-10, Pseudonocardia sp. AL041005-10
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