STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND67665.1Pfam: MerR HTH family regulatory protein; PRINTS: MerR bacterial regulatory protein HTH signature; Pfam: TipAS antibiotic-recognition domain; SMART: helix_turn_helix, mercury resistance. (342 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.609
AND70453.1
TIGRFAM: GlnA: glutamine synthetase, type I; Pfam: Glutamine synthetase, catalytic domain; Pfam: Glutamine synthetase, beta-Grasp domain.
  
 
 0.537
AND68057.1
Cytochrome C biogenesis protein; Pfam: DnaJ domain; PRINTS: DnaJ domain signature; SMART: DnaJ molecular chaperone homology domain; Pfam: DnaJ C terminal domain.
  
 
 0.526
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.526
AND70985.1
Hypothetical protein; Pfam: DnaJ domain.
  
 
 0.526
AND70395.1
ATPase; SMART: Histidine kinase-like ATPases; SMART: His Kinase A (phosphoacceptor) domain; Pfam: PAS fold; PRINTS: Bacterial sensor protein C-terminal signature; SMART: cheY-homologous receiver domain; Pfam: His Kinase A (phospho-acceptor) domain; Pfam: Response regulator receiver domain; Pfam: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 
 0.505
AND70986.1
Hypothetical protein; TIGRFAM: AA-adenyl-dom: amino acid adenylation domain; Pfam: AMP-binding enzyme C-terminal domain; Pfam: Phosphopantetheine attachment site; Pfam: AMP-binding enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 
 0.459
AND68484.1
Pfam: His Kinase A (phospho-acceptor) domain; SMART: cheY-homologous receiver domain; Pfam: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; SMART: His Kinase A (phosphoacceptor) domain; SMART: Histidine kinase-like ATPases; Pfam: PAS domain; TIGRFAM: sensory_box: PAS domain S-box protein; Pfam: Response regulator receiver domain; Pfam: GAF domain; SMART: PAS domain; PRINTS: Bacterial sensor protein C-terminal signature.
   
 
 0.445
AND68639.1
Histidine kinase; SMART: Domain present in phytochromes and cGMP-specific phosphodiesterases; TIGRFAM: sensory_box: PAS domain S-box protein; PRINTS: Bacterial sensor protein C-terminal signature; SMART: PAS domain; SMART: Histidine kinase-like ATPases; SMART: Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Pfam: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Pfam: PAS fold; Pfam: His Kinase A (phospho-acceptor) domain; Pfam: CHASE domain; SMART: His Kinase A (phosphoacceptor) domain; Pfam: GAF domain.
   
 
 0.442
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.440
Your Current Organism:
Dyella thiooxydans
NCBI taxonomy Id: 445710
Other names: D. thiooxydans, Dyella sp. ATSB10, Dyella thiooxydans Anandham et al. 2011, KACC 12756, LMG 24673, LMG:24673, strain ATSB10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.