STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
surEStationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (259 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.947
guaB
Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.945
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.942
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
 
  
 0.936
purH
IMP cyclohydrolase; Pfam: MGS-like domain; Pfam: AICARFT/IMPCHase bienzyme; SMART: MGS-like domain; TIGRFAM: purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; SMART: AICARFT/IMPCHase bienzyme.
     
 0.933
cmk
Pfam: Cytidylate kinase; TIGRFAM: cmk: cytidylate kinase.
    
 0.926
AND68081.1
PRINTS: Fumarate lyase superfamily signature; Pfam: Adenylosuccinate lyase C-terminal; TIGRFAM: purB: adenylosuccinate lyase; Pfam: Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.925
pyrF
Pfam: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: pyrF_sub2: orotidine 5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 0.920
AND70536.1
Hypothetical protein; Pfam: Glutamine amidotransferase class-I.
    
 0.920
AND70586.1
5'-nucleotidase; Pfam: Calcineurin-like phosphoesterase; PRINTS: Apyrase family signature; Pfam: 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
     
 0.918
Your Current Organism:
Dyella thiooxydans
NCBI taxonomy Id: 445710
Other names: D. thiooxydans, Dyella sp. ATSB10, Dyella thiooxydans Anandham et al. 2011, KACC 12756, LMG 24673, LMG:24673, strain ATSB10
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