STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (248 aa)    
Predicted Functional Partners:
AND70385.1
TIGRFAM: dnan: DNA polymerase III, beta subunit; Pfam: DNA polymerase III beta subunit, N-terminal domain; Pfam: DNA polymerase III beta subunit, C-terminal domain; SMART: DNA polymerase III beta subunit; Pfam: DNA polymerase III beta subunit, central domain.
   
 
 0.833
AND69980.1
Histidine kinase; SMART: cheY-homologous receiver domain; Pfam: Response regulator receiver domain.
 
     0.825
AND70349.1
TIGRFAM: exoDNase_III: exodeoxyribonuclease III; Pfam: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: xth: exodeoxyribonuclease III (xth).
   
 0.777
AND70528.1
Catabolite repression control protein; Pfam: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: xth: exodeoxyribonuclease III (xth); TIGRFAM: exoDNase_III: exodeoxyribonuclease III.
   
 0.777
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.677
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
      0.565
AND69981.1
Hypothetical protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.560
ftsE
Cell division protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.560
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.541
rpoH
RNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
       0.519
Your Current Organism:
Dyella thiooxydans
NCBI taxonomy Id: 445710
Other names: D. thiooxydans, Dyella sp. ATSB10, Dyella thiooxydans Anandham et al. 2011, KACC 12756, LMG 24673, LMG:24673, strain ATSB10
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