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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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pfp6-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (562 aa)    
Predicted Functional Partners:
Emin_1116
PFAM: phosphoglucose isomerase (PGI); KEGG: aba:Acid345_2810 transaldolase; Belongs to the GPI family.
  
 0.959
Emin_0353
Fructose-1,6-bisphosphate aldolase, class II; KEGG: pca:Pcar_2253 fructose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
  
 
 0.926
Emin_0355
PFAM: Transketolase central region; KEGG: mxa:MXAN_7358 transketolase; Belongs to the transketolase family.
  
 0.923
Emin_0367
Extracellular sugar kinase family; PFAM: PfkB domain protein; KEGG: pdi:BDI_3374 putative fructokinase.
  
 0.918
pfkA
6-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
     
 
0.900
Emin_0558
KEGG: rru:Rru_A2465 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.752
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.600
Emin_0806
Pyruvate:ferredoxin oxidoreductase; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gur:Gura_4330 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
 0.597
Emin_1350
TIGRFAM: PTS system, glucose subfamily, IIA subunit; phosphocarrier, HPr family; phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; sugar-specific permease EIIA 1 domain; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: pfl:PFL_4931 phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
  
  
 0.594
tpiA
Glycolysis; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.585
Your Current Organism:
Elusimicrobium minutum
NCBI taxonomy Id: 445932
Other names: E. minutum Pei191, Elusimicrobium minutum Pei191, Elusimicrobium minutum str. Pei191, Elusimicrobium minutum strain Pei191
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