node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IW15_05510 | IW15_06330 | IW15_05510 | IW15_06330 | UDP-2,3-diacylglucosamine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
IW15_05510 | IW15_18830 | IW15_05510 | IW15_18830 | UDP-2,3-diacylglucosamine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.410 |
IW15_05510 | IW15_19010 | IW15_05510 | IW15_19010 | UDP-2,3-diacylglucosamine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.934 |
IW15_05510 | lpxC | IW15_05510 | IW15_06315 | UDP-2,3-diacylglucosamine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | hydroxymyristoyl-ACP dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.626 |
IW15_05510 | lpxD | IW15_05510 | IW15_06310 | UDP-2,3-diacylglucosamine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.925 |
IW15_06320 | IW15_06330 | IW15_06320 | IW15_06330 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
IW15_06320 | IW15_11625 | IW15_06320 | IW15_11625 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 0.810 |
IW15_06320 | IW15_12520 | IW15_06320 | IW15_12520 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.869 |
IW15_06320 | IW15_18830 | IW15_06320 | IW15_18830 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.829 |
IW15_06320 | IW15_19010 | IW15_06320 | IW15_19010 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.963 |
IW15_06320 | kdsB | IW15_06320 | IW15_11725 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.831 |
IW15_06320 | lpxC | IW15_06320 | IW15_06315 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | hydroxymyristoyl-ACP dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.998 |
IW15_06320 | lpxD | IW15_06320 | IW15_06310 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.967 |
IW15_06320 | lpxK | IW15_06320 | IW15_07855 | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.833 |
IW15_06330 | IW15_05510 | IW15_06330 | IW15_05510 | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-2,3-diacylglucosamine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
IW15_06330 | IW15_06320 | IW15_06330 | IW15_06320 | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.922 |
IW15_06330 | IW15_11625 | IW15_06330 | IW15_11625 | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 0.753 |
IW15_06330 | IW15_12520 | IW15_06330 | IW15_12520 | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.849 |
IW15_06330 | IW15_18830 | IW15_06330 | IW15_18830 | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.764 |
IW15_06330 | IW15_19010 | IW15_06330 | IW15_19010 | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.982 |