STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73354.1ThiF family protein; KEGG: hpa:HPAG1_0740 6.5e-25 molybdopterin biosynthesis protein; COG: COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Psort location: Cytoplasmic, score: 8.87. (224 aa)    
Predicted Functional Partners:
thiF
Thiamine biosynthesis protein ThiF; KEGG: pha:PSHAa0485 1.6e-21 thiF; adenylyltransferase K03148; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
 
0.778
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
       0.759
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
    
 0.746
thiS
COG: COG2104 Sulfur transfer protein involved in thiamine biosynthesis; Psort location: Cytoplasmic, score: 8.87.
  
  0.684
EDS73353.1
Hypothetical protein; KEGG: mpe:MYPE6470 4.8e-24 parC; DNA topoisomerase IV subunit A K02621; COG: COG5651 PPE-repeat proteins.
       0.618
EDS72069.1
FAD dependent oxidoreductase; KEGG: ctc:CTC00417 6.7e-87 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating).
    
  0.596
EDS72163.1
KEGG: cbu:CBU_0587 6.4e-11 glpE protein, putative K02439; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.595
lepB
Signal peptidase I; KEGG: bsu:BG10515 3.2e-32 sipS; type I signal peptidase K03100; COG: COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
       0.566
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
  0.472
EDS73102.1
Aminotransferase, class V; KEGG: tte:TTE1663 8.7e-78 nifS; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
    
 0.409
Your Current Organism:
Anaerofustis stercorihominis
NCBI taxonomy Id: 445971
Other names: A. stercorihominis DSM 17244, Anaerofustis stercorihominis DSM 17244, Anaerofustis stercorihominis str. DSM 17244, Anaerofustis stercorihominis strain DSM 17244
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