STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS72862.1Recombination factor protein RarA; KEGG: ava:Ava_B0112 1.8e-116 ATPase K00961:K07478; COG: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; Psort location: Cytoplasmic, score: 8.87. (482 aa)    
Predicted Functional Partners:
EDS73344.1
Macro domain protein; KEGG: bur:Bcep18194_A6181 5.7e-42 Appr-1-p processing enzyme family K00985; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: Cytoplasmic, score: 8.87.
      0.902
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.678
EDS71411.1
HAD hydrolase, family IIA; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family.
 
      0.674
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.618
EDS72326.1
FtsK/SpoIIIE family protein; KEGG: pen:PSEEN2212 1.2e-103 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score: 7.63; Belongs to the FtsK/SpoIIIE/SftA family.
    0.616
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.525
cinA
Competence/damage-inducible domain protein CinA; KEGG: mmu:319945 6.8e-08 Flad1; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) K00953; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
     
 0.480
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.455
holB
KEGG: deh:cbdb_A509 1.1e-28 holB; DNA polymerase III, delta prime subunit K02341; COG: COG0470 ATPase involved in DNA replication.
   
   0.407
rpsP
Ribosomal protein S16; KEGG: ctc:CTC01994 0.0068 deoxyribose-phosphate aldolase K01619; COG: COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
 
     0.400
Your Current Organism:
Anaerofustis stercorihominis
NCBI taxonomy Id: 445971
Other names: A. stercorihominis DSM 17244, Anaerofustis stercorihominis DSM 17244, Anaerofustis stercorihominis str. DSM 17244, Anaerofustis stercorihominis strain DSM 17244
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