STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribFRiboflavin biosynthesis protein RibF; KEGG: cpe:CPE1682 8.3e-57 ribC; riboflavin kinase / FMN adenylyltransferase K00861:K00953; COG: COG0196 FAD synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the ribF family. (304 aa)    
Predicted Functional Partners:
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.989
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
 
   
 0.888
cmk
Cytidylate kinase; KEGG: fnu:FN1607 5.3e-55 cytidylate kinase K00945; COG: COG0283 Cytidylate kinase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.882
EDS71502.1
Hypothetical protein; COG: COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; Psort location: Cytoplasmic, score: 8.87.
 
    0.852
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
    0.825
EDS71499.1
DHHA1 domain protein; KEGG: tma:TM0715 2.6e-10 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; COG: COG0618 Exopolyphosphatase-related proteins; Psort location: Cytoplasmic, score: 8.87.
       0.819
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
    0.815
EDS72116.1
Nitroreductase family protein; KEGG: fnu:FN1223 1.7e-33 oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase K00357; COG: COG0778 Nitroreductase.
    
 0.793
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.753
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
    0.732
Your Current Organism:
Anaerofustis stercorihominis
NCBI taxonomy Id: 445971
Other names: A. stercorihominis DSM 17244, Anaerofustis stercorihominis DSM 17244, Anaerofustis stercorihominis str. DSM 17244, Anaerofustis stercorihominis strain DSM 17244
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.