STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)    
Predicted Functional Partners:
EDS73598.1
Phosphoribulokinase/uridine kinase family protein; KEGG: tte:TTE1778 2.2e-111 udk; uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: CytoplasmicMembrane, score: 7.80.
  
 0.965
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.963
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.950
pyrF
KEGG: ctc:CTC02381 1.6e-76 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.924
rpiB
KEGG: bcl:ABC3865 3.1e-41 ribose 5-phosphate isomerase B K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.911
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
    
 0.853
pyrR
Phosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.820
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.808
EDS71818.1
4Fe-4S binding domain protein; KEGG: mmp:MMP0824 2.4e-16 vhcB; coenzyme F420-non-reducing hydrogenase subunit beta; COG: COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB; Psort location: Cytoplasmic, score: 8.87.
    
  0.788
deoD
KEGG: pha:PSHAb0082 2.3e-68 deoD; purine nucleoside phosphorylase (inosine phosphorylase) (PNP) K03784; COG: COG0813 Purine-nucleoside phosphorylase.
    
  0.785
Your Current Organism:
Anaerofustis stercorihominis
NCBI taxonomy Id: 445971
Other names: A. stercorihominis DSM 17244, Anaerofustis stercorihominis DSM 17244, Anaerofustis stercorihominis str. DSM 17244, Anaerofustis stercorihominis strain DSM 17244
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