node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDS71820.1 | EDS72218.1 | ANASTE_01523 | ANASTE_01928 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.769 |
EDS71820.1 | carA | ANASTE_01523 | ANASTE_01933 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: cpr:CPR_2577 6.3e-107 carA; carbamoyl-phosphate synthase, small subunit K01956; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | 0.790 |
EDS71820.1 | carB | ANASTE_01523 | ANASTE_01934 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: cpe:CPE2572 0. carB; carbamoyl-phosphate synthetase catalytic subunit K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score: 8.87. | 0.795 |
EDS71820.1 | gltA | ANASTE_01523 | ANASTE_01524 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: tte:TTE0567 3.0e-155 gltD; NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.999 |
EDS71820.1 | pyrB | ANASTE_01523 | ANASTE_01926 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: cno:NT01CX_0395 1.6e-110 pyrB; aspartate carbamoyltransferase K00608; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.746 |
EDS71820.1 | pyrD | ANASTE_01523 | ANASTE_01931 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.983 |
EDS71820.1 | pyrE | ANASTE_01523 | ANASTE_01932 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.792 |
EDS71820.1 | pyrF | ANASTE_01523 | ANASTE_01929 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: ctc:CTC02381 1.6e-76 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.779 |
EDS72218.1 | EDS71820.1 | ANASTE_01928 | ANASTE_01523 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0467 1.6e-67 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.769 |
EDS72218.1 | EDS72220.1 | ANASTE_01928 | ANASTE_01930 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0392 1.1e-45 dihydroorotate dehydrogenase electron transfer subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.65. | 0.998 |
EDS72218.1 | carA | ANASTE_01928 | ANASTE_01933 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | KEGG: cpr:CPR_2577 6.3e-107 carA; carbamoyl-phosphate synthase, small subunit K01956; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | 0.997 |
EDS72218.1 | carB | ANASTE_01928 | ANASTE_01934 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | KEGG: cpe:CPE2572 0. carB; carbamoyl-phosphate synthetase catalytic subunit K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score: 8.87. | 0.997 |
EDS72218.1 | gltA | ANASTE_01928 | ANASTE_01524 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | KEGG: tte:TTE0567 3.0e-155 gltD; NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.623 |
EDS72218.1 | guaA | ANASTE_01928 | ANASTE_01808 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.647 |
EDS72218.1 | pyrB | ANASTE_01928 | ANASTE_01926 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | KEGG: cno:NT01CX_0395 1.6e-110 pyrB; aspartate carbamoyltransferase K00608; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
EDS72218.1 | pyrD | ANASTE_01928 | ANASTE_01931 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.998 |
EDS72218.1 | pyrE | ANASTE_01928 | ANASTE_01932 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.975 |
EDS72218.1 | pyrF | ANASTE_01928 | ANASTE_01929 | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | KEGG: ctc:CTC02381 1.6e-76 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.980 |
EDS72220.1 | EDS72218.1 | ANASTE_01930 | ANASTE_01928 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0392 1.1e-45 dihydroorotate dehydrogenase electron transfer subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.65. | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.998 |
EDS72220.1 | carA | ANASTE_01930 | ANASTE_01933 | Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0392 1.1e-45 dihydroorotate dehydrogenase electron transfer subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.65. | KEGG: cpr:CPR_2577 6.3e-107 carA; carbamoyl-phosphate synthase, small subunit K01956; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | 0.965 |