STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crgAProtein of unknown function UPF0233; Involved in cell division; Belongs to the CrgA family. (88 aa)    
Predicted Functional Partners:
Amir_5755
PFAM: DivIVA family protein; KEGG: hypothetical protein.
  
   
 0.859
Amir_0023
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; KEGG: penicillin-binding protein 2; K05515 penicillin binding protein 2.
   
 
 0.819
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.747
Amir_5772
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ppd:Ppro_3295 peptidoglycan glycosyltransferase.
   
 
 0.747
Amir_0015
Hypothetical protein.
 
   
 0.737
ftsQ
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
    
 
 0.736
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
      
 0.713
Amir_0026
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: mxa:MXAN_4649 FHA domain protein.
  
  
 0.623
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
      
 0.616
Amir_6445
Hypothetical protein.
  
     0.607
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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