STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_0119PFAM: FAD dependent oxidoreductase; HI0933 family protein; KEGG: sus:Acid_5855 FAD dependent oxidoreductase. (395 aa)    
Predicted Functional Partners:
Amir_0120
PFAM: Luciferase-like monooxygenase; KEGG: rpb:RPB_4411 luciferase-like.
       0.778
Amir_0121
TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; KEGG: mno:Mnod_7133 Cof-like hydrolase.
       0.581
Amir_5693
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
  
  
 0.571
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  
 0.527
Amir_6253
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region; catalytic domain of components of various dehydrogenase complexes; KEGG: sus:Acid_5307 alpha-ketoglutarate decarboxylase.
  
  
 0.500
Amir_1492
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
      
 0.499
Amir_6112
TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; KEGG: dde:Dde_1180 phosphoenolpyruvate--protein phosphotransferase.
     
 0.467
Amir_6664
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: eba:ebA3149 2-oxoglutarate ferredoxin oxidoreductase alpha subunit.
     
 0.452
Amir_0372
PFAM: protein of unknown function DUF1212; KEGG: rpt:Rpal_1546 protein of unknown function DUF1212.
       0.442
Amir_5854
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cvi:CV_0813 uroporphyrin-III C- methyltransferase.
       0.438
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (14%) [HD]