STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_0199PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: aba:Acid345_1672 methyl-accepting chemotaxis sensory transducer. (532 aa)    
Predicted Functional Partners:
Amir_2325
PFAM: CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; ATP- binding region ATPase domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: aba:Acid345_1524 CheA signal transduction histidine kinases.
 
 0.991
Amir_2324
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: aba:Acid345_1525 CheW protein.
 
 0.986
Amir_2320
KEGG: aba:Acid345_1529 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; Methyltransferase type 12; SMART: MCP methyltransferase CheR-type.
 0.983
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.982
Amir_2319
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: aba:Acid345_1527 response regulator receiver protein, CheY.
 
 0.978
Amir_2317
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dds:Ddes_0324 response regulator receiver protein.
 
 0.976
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
 
 
 0.754
Amir_2334
PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; KEGG: hhe:HH1147 flagellar motor switch protein FliM.
 
  
 0.641
Amir_2346
TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; KEGG: bha:BH2457 flagellar motor switch protein G.
 
  
 0.598
Amir_0198
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pca:Pcar_1336 putative methyl-accepting chemotaxis protein (MCP).
 
    
0.595
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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