STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_0205Transcriptional regulator, SARP family; PFAM: transcriptional activator domain; TPR repeat- containing protein; Tetratricopeptide TPR_4; NB-ARC domain protein; transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: scl:sce5225 protein kinase. (1088 aa)    
Predicted Functional Partners:
Amir_4694
Transcriptional regulator, SARP family; PFAM: transcriptional activator domain; transcriptional regulator domain protein; KEGG: sme:SMa0464 adenylate/guanylate cyclase.
 
 
0.654
Amir_0651
Hypothetical protein; KEGG: WIP homolog.
  
     0.646
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
   
 
 0.632
Amir_0576
Transcriptional regulator, SARP family; PFAM: transcriptional activator domain; Tetratricopeptide TPR_4; TPR repeat-containing protein; NB- ARC domain protein; transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: scl:sce5225 protein kinase.
 
  
0.629
Amir_3736
Putative PAS/PAC sensor protein; KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
  
  
 0.597
Amir_6431
PFAM: WD-40 repeat protein; pentapeptide repeat protein; SMART: WD-40 repeat protein; KEGG: scl:sce3623 hypothetical protein.
  
 0.596
Amir_6778
KEGG: pag:PLES_38291 hypothetical protein.
  
     0.589
Amir_6301
Mn2+dependent serine/threonine protein kinase; PFAM: aminoglycoside phosphotransferase; KEGG: mch:Mchl_2091 aminoglycoside phosphotransferase.
  
     0.568
Amir_3434
PFAM: regulatory protein TetR; KEGG: ade:Adeh_2880 TetR family transcriptional regulator.
  
    0.535
Amir_2068
PFAM: protein of unknown function DUF742.
  
     0.516
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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